Abstract
Neutrophils from pig blood were used as a model system to investigate the optical communication between cells. It was found that neutrophils stimulated to undergo respiratory burst can activate a second, chemically separated, but optically coupled population of neutrophils. The response of the latter was visualized as a temporary rising of their low-level chemiluminescence and an enhanced generation of superoxide radicals detected by both the reduction of ferricytochrome c and spin trapping. The results provide evidence that a long-range optical coupling of biological significance between living cells exists.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Synder, S. H., Scient. Am.253 (1985) 114.
Gurwitsch, A. G., and Gurwitsch, L. D., Die Mitogenetische Strahlung, ihre physikalisch-chemischen Grundlagen und ihre Anwendung auf die Biologie und Medizin. G. Fischer, Jena 1959.
Rahn, O., Invisible Radiation of Organisms. Borntraeger, Berlin 1936.
Popp, F. A., in: Molecular Base of Malignancy, p. 47. Eds. E. Deutsch, K. Moser, H. Rainer, and A. Stacher, Georg Thieme, Stuttgart 1976.
Kaznacheev, V. P., and Mikhailova, L. P., Ultraweak Radiation in Intercellular Interactions Nauka, Novosibirsk 1981 (in Russian).
Allen, R. C., Stjernholm, R. L., and Steele, R. H., Biochem. biophys. Res. Commun.47 (1972) 679.
Allen, R. C., Yevich, S. J., Orth, R. W., and Steele, R. H., Biochem. biophys. Res. Commun.60 (1974) 909.
Dechatelet, L. R., Shirley, P. S., and Johnston, R. B. Jr., Blood47 (1976) 545.
Sbarra, J., and Karnofsky, M. L., J. biol. Chem.234 (1959) 1355.
Rossi, F., and Zatti, M., Br. J. expl. Path.45 (1964) 548.
Allen, R. C., Photochem. Photobiol.30 (1979) 157.
Boveris, A., Cadenas, E., and Chance, B., Fedn Proc.40 (1981) 195.
Ruth, B., in: Electromagnetic Bio-Information (2nd edn), p. 128. Eds F. A. Popp, U. Warnke, H. L. Koenig and W. Peschka. Urban & Schwarzenberg, Muenchen-Wien-Baltimore 1989.
O'Brien, P. J., Meth. Enzym.105 (1984) 370.
Babior, B. M., J. clin. Invest.73 (1984) 599.
Johansson, A., and Dahlgen, C., J. Leukocyte Biol.45 (1989) 444.
Halliwell, B., and Gutteridge, J. M. C., Meth. Enzym.186 (1990) 1.
Dicke, R. H., Phys. Rev.93 (1954) 99.
Popp, F. A., in: Recent Advance in Biophoton Research and its Application, p. 357. Eds F. A. Popp, K. H. Li and Q. Gu. World Scientific, Singapore-New Jersey-London-Hong Kong 1992.
Galantsev, V. P., Kovalenko, S. G., Moltchanov, A. A., and Prutskov, V. I., Experientia49 (1993) 870.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Shen, X., Mei, W. & Xu, X. Activation of neutrophils by a chemically separated but optically coupled neutrophil population undergoing respiratory burst. Experientia 50, 963–968 (1994). https://doi.org/10.1007/BF01923488
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01923488