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Experientia

, Volume 47, Issue 10, pp 1063–1066 | Cite as

Reversible juvenile hormone inhibition of ecdysteroid and juvenile hormone synthesis by the ring gland ofDrosophila melanogaster

  • D. S. Richard
  • L. I. Gilbert
Research Articles

Abstract

Juvenile hormone bisepoxide (JHB3) and juvenile hormone III (JH III) both inhibited the in vitro production of ecdysteroids by ring glands and brain-ring gland complexes from third instar post-feeding larvae ofDrosophila melanogaster in a reversible manner, although JHB3 had greater efficacy. The JH III and JHB3 precursor, methyl farnesoate, did not affect ecdysteroid production. The in vitro synthesis of total detectable JH (JHB3+JH III+methyl farnesoate) by the corpus allatum portion of the isolated ring gland was also inhibited reversibly in the presence of exogenous JHB3 and JH III, but not by methyl farnesoate. These data indicating negative feedback are in agreement with the accepted dogma of endocrine gland regulation.

Key words

Juvenile hormone corpus allatum prothoracic gland dipteran endocrinology 

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Copyright information

© Birkhäuser Verlag 1991

Authors and Affiliations

  • D. S. Richard
    • 1
  • L. I. Gilbert
    • 1
  1. 1.Department of Biology, CB No. 3280 Coker HallUniversity of North Carolina at Chapel HillChapel HillUSA

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