Experientia

, Volume 31, Issue 12, pp 1391–1392 | Cite as

Extracellular Ca2+ and Mg2+ and cellular metabolism of phospholipids

  • L. G. Anghileri
Specialia Chimica, Biochimica
  • 8 Downloads

Summary

High extracellular concentration of Ca2+ inhibits the incorporation of32P into the cellular phospholipids. This effect is more significant in neoplastic than in normal cells, and it is accompanied by an increase of the percentual incorporation into the lecithin fraction.

Keywords

Normal Cell Lecithin Cellular Metabolism Extracellular Concentration Cellular Phospholipid 

References

  1. 1.
    L. G. Abood, I. Koyama andH. Kimizuka, Nature, Lond.197, 367 (1963).Google Scholar
  2. 2.
    A. M. Shanes, Pharmac. Rev.10, 59 (1958).Google Scholar
  3. 3.
    E. Schoffeniels, inCellular Aspects of Membrane Permeability (Pergamon Press, New York 1967), p. 82.Google Scholar
  4. 4.
    C. Horvath andM. Sovak, Biochim. biophys. Acta298, 850 (1973).PubMedGoogle Scholar
  5. 5.
    D. P. Yang andH. J. Morton, J. natn. Cancer Inst. USA46, 505 (1971).Google Scholar
  6. 6.
    D. P. Anghileri, Oncology29, 152 (1974).PubMedGoogle Scholar
  7. 7.
    D. N. Rhodes andC. H. Lea, Biochem. J.65, 526 (1957).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1975

Authors and Affiliations

  • L. G. Anghileri
    • 1
  1. 1.Innere Klinik und Poliklinik (Tumorforschung)Klinikum der GHS EssenEssen(German Federal Republic, BRD)

Personalised recommendations