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Radioimmunoassay of polyacrylamide

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Summary

Antiserum to polyacrylamide has been produced in rabbits. It can be used in a sensitive radioimmunoassay for quantitation of polyacrylamide at very low concentrations. This novel approach to the analysis of a synthetic, biologically inactive, hydrocarbon polymer has potentially widespread implications, for example, in the downstream measurement of flocculating agents used in water purification treatments.

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References

  1. R. S. Yalow and S. A. Berson, in: Principles of Competitive Protein Binding Assays, p. 1. Ed. W. D. Odell and W. H. Daughaday, J. B. Lippincott Co., Philadelphia 1971.

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  2. G. T. Davis and D. H. Rosenblatt, Tetrahedron Lett.1968, 4085.

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Authors and Affiliations

  1. Bio-Science Laboratories, 7600 Tyrone Avenue, 91405, Van Nuys, California

    Patricia A. Drewes, A. O. Kamp & J. W. Winkelman

  2. Analytical Laboratories, Dow Chemical Company, 48640, Midland, Michigan, USA

    Patricia A. Drewes, A. O. Kamp & J. W. Winkelman

Authors
  1. Patricia A. Drewes
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  2. A. O. Kamp
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  3. J. W. Winkelman
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Additional information

Acknowlegment. We thank L. P. McCarty for coordination of the project, F. A. Blanchard for synthesis of the14C-PAA, and C. Brown and J. Cuan for technical assistance in the biological studies.

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Drewes, P.A., Kamp, A.O. & Winkelman, J.W. Radioimmunoassay of polyacrylamide. Experientia 34, 316–318 (1978). https://doi.org/10.1007/BF01923008

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  • DOI: https://doi.org/10.1007/BF01923008

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