, Volume 34, Issue 9, pp 1171–1172 | Cite as

Effect of blood pH on anionic ferritin transport through rat aortic endothelium

  • J. R. Fraser
  • P. H. Oliveira
  • I. Hüttner


Acute lowering of blood pH between 7.4 and 6.9 in rats by ventilation with 10 or 20% CO2 does not increase the passage of ferritin molecules across the aortic endothelium. These results do not rule out alteration of endothelial permeability to anionic macromolecules in local circulatory disturbances when blood pH drops to levels much lower than 6.9.


Permeability Macromolecule Ferritin Endothelial Permeability Circulatory Disturbance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 4.
    E. Skutelsky and D. Danon, J. Cell Biol.71, 232 (1976).PubMedGoogle Scholar
  2. 5.
    E. Skutelsky, Z. Rudich and D. Danon, Thromb. Res.7, 623 (1975).PubMedGoogle Scholar
  3. 6.
    H. G. Rennke, R.S. Contran and M.A., Venkatachalam. J. Cell Biol.67, 638 (1975).PubMedGoogle Scholar
  4. 7.
    H.G. Rennke and M.A. Venkatachalam, Kidney International11, 44 (1977).PubMedGoogle Scholar
  5. 8.
    L.C. Arminger, and J.B. Gavin, Lab. Invest.33, 51 (1975).PubMedGoogle Scholar
  6. 9.
    I. Hüttner, M. Boutet, G. Rona, and R.H. More, Lab. Invest.29, 536 (1973).PubMedGoogle Scholar
  7. 10.
    L. Appelgren, in: Microcirculation, vol. 2, p. 113. Ed. J. Grayson and W. Zingg Plenum Press, New York. 1976.Google Scholar
  8. 11.
    I.McA. Ledingham, J. R. Parratt and J.P. Vance, in: Conference on ‘Shock’, p. 13. Ed. I.McA. Ledingham and T.A. McAllister, The C.V. Mosby Co., St. Louis 1972.Google Scholar
  9. 12.
    J.W. Drysdale and J. Kirby, Biochim. biophys. Acta207, 256 (1970).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • J. R. Fraser
    • 1
  • P. H. Oliveira
    • 1
  • I. Hüttner
    • 1
  1. 1.Department of PathologyMcGill UniversityMontrealCanada

Personalised recommendations