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New utilizations of the phenacyloxy protecting group in peptide synthesis

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Zusammenfassung

Es wird über weitere Verwendungsmöglichkeiten der Phenacyloxy-Gruppe in der Peptidsynthese berichtet. Phenacyloxyester reagieren leicht mit Hydrogencyanid unter Bildung der entsprechenden 2-Cyano-2-phenyl-vinyl-ester, welch letztere Derivate sich als gute Acylierungsmittel erwiesen.

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Author notes

  1. L. R. Treiber

    Present address: AFC, Astra Pharmaceuticals Co., S-15185, Södertälje, Sweden

Authors and Affiliations

  1. Division of Macromolecular Science, Case Western Reserve University, 802 Olin Building, 44106, Cleveland, Ohio, USA

    L. R. Treiber

Authors
  1. L. R. Treiber
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Additional information

Acknowledgement. I thank ProfessorM. Bodanszky for valuable discussions and advice. Financial support for the research has been provided by the National Science Foundation.

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Treiber, L.R. New utilizations of the phenacyloxy protecting group in peptide synthesis. Experientia 29, 1335–1337 (1973). https://doi.org/10.1007/BF01922801

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