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Protective effect of tannic acid in mice receiving dietary lead

Summary

Mice fed a diet containing both tannic acid and lead acetate showed increased weight gain and greater fecundity when compared with those on a diet containing lead acetate alone. The most significant improvement was provided by adding 2% tannic acid (wt/wt) to ground food containing 3% lead acetate. The affinity of tannic acid for heavy metals is suggested as a reason for this protective effect.

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Peaslee, M.H., Einhellig, F.A. Protective effect of tannic acid in mice receiving dietary lead. Experientia 33, 1206 (1977). https://doi.org/10.1007/BF01922331

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  • DOI: https://doi.org/10.1007/BF01922331

Keywords

  • Acetate
  • Heavy Metal
  • Weight Gain
  • Protective Effect
  • Tannic Acid