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Neurochemical correlates of alloxan diabetes: Gamma amino butyric acid of amphibian brain

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Summary

The levels of gamma aminobutyric acid decreased, while glutamic acid and aspartic acid levels increased in the forebrain, and decreased in the mid and hind brain regions of frog, Rana cyanophlictis during alloxan diabetes. Since glutamic acid and GABA are intimately involved in the central nervous system (CNS) functions, the alterations occurring in their levels during alloxan diabetes may be significant in bringing about a correlation between the diabetic state and the altered functional dynamics of the CNS.

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Authors and Affiliations

  1. Deaartment of Zoology, Bangalore University, 560001, Bangalore, India

    Nayeemunnisa & J. S. Nagaraj

Authors
  1. Nayeemunnisa
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  2. J. S. Nagaraj
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The authors thank Dr A. R. Kasturi Bai for the facilities to conduct the study.

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Nayeemunnisa, Nagaraj, J.S. Neurochemical correlates of alloxan diabetes: Gamma amino butyric acid of amphibian brain. Experientia 33, 1186–1187 (1977). https://doi.org/10.1007/BF01922318

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