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Reductive dechlorination of chlorobiphenylols by rats

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  • Chimica, Biochimica
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Summary

Dechlorinated products were isolated from the urine of rats that were administered chlorobiphenylols, the primary hydroxylated metabolites of PCB in mammals. The mechanism of chlorine loss from chlorobiphenylols is different from the mechanism of dechlorination via arene oxides whereby concomitant hydroxylation is always observed.

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Author information

Authors and Affiliations

  1. Laboratory of Environmental Chemistry, University of Amsterdam, Nieuwe Achtergracht 166, Amsterdam, the Netherlands

    M. Th. M. Tulp, W. A. Bruggeman & O. Hutzinger

Authors
  1. M. Th. M. Tulp
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  2. W. A. Bruggeman
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  3. O. Hutzinger
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Additional information

A fellowship to the first author by the Organisation for the Advancement of Pure Research (stichting Z. W. O., The Netherlands) is gratefully acknowledged.

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Tulp, M.T.M., Bruggeman, W.A. & Hutzinger, O. Reductive dechlorination of chlorobiphenylols by rats. Experientia 33, 1134–1136 (1977). https://doi.org/10.1007/BF01922284

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  • DOI: https://doi.org/10.1007/BF01922284

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