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Experientia

, Volume 33, Issue 4, pp 531–533 | Cite as

Suppression of the secondary immune response by specific antibody, when given together with the secondary antigenic stimulus

  • H. Finger
  • H. Hof
  • C.-H. Wirsing
  • P. Emmerling
Specialia

Summary

It is generally believed that antibody-mediated immunosuppression can be only produced in non-primed individuals, and that this applies both to experimental animals and Rh-negative women at risk. However, in this paper it is reported that the additional injection of 0.2 ml of an antiserum to sheep erythrocytes (SE) together with a secondary antigenic stimulus of 108 SE into mice, primarily immunized by a tiny dose of 5×105 SE 28 days before, was capable of producing effective suppression of the secondary immune response.

Keywords

Immune Response Experimental Animal Specific Antibody Effective Suppression Sheep Erythrocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • H. Finger
    • 1
    • 2
  • H. Hof
    • 1
    • 2
  • C.-H. Wirsing
    • 1
    • 2
  • P. Emmerling
    • 1
    • 2
  1. 1.Institute of HygieneMunicipal Hospital of KrefeldKrefeld 1(Federal Republic of Germany)
  2. 2.Institute of Hygiene and MicrobiologyUniversity of WürzburgBRD

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