Summary
Intravenously administered light lanthanons change spectral interactions in rat liver not only by decreasing the concentration of cytochrome P-450, but they also cause a qualitative change in the cytochrome P-450 molecule or its microenvironment.
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The authors wish to thank Mrs Irs Baar, Mrs Brigitte Schröder and Mrs Brunhilde Enkemann for their valuable technical assistance.
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P. Arvela is a fellow of the Alexander-von-Humboldt-Stiftung.
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Arvela, P., Grajewski, O., v. Lehmann, B. et al. Effect of lanthanons on substrate-induced difference spectra in rat liver microsomes. Experientia 33, 491–493 (1977). https://doi.org/10.1007/BF01922228
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DOI: https://doi.org/10.1007/BF01922228