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Role of Friend-associated lymphatic leukemia virus in immunization against Friend leukemia complex

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Summary

Mice inoculated with Friend leukemia complex (FLC) pretreated with concanavalin A are resistant to FLC challenge only when they have become infected with the FLC-associated lymphatic leukemia virus (LLV). In interpreting states of resistance to FLC induced by various immunizing procedures, the possibility that immunity is sustained by an unrecognized LLV infection should always be considered.

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Supported by a grant from the Italian National Research Council.

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Bendinelli, M. Role of Friend-associated lymphatic leukemia virus in immunization against Friend leukemia complex. Experientia 33, 455–456 (1977). https://doi.org/10.1007/BF01922207

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