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Transcriptional effects of 5-bromo-2′-deoxyuridine in post-implantation mouse embryos

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Summary

Administration of 5-bromo-2′-deoxyuridine to pregnant mice on the 6th day p.c. brings about significant reduction in the incorporation of3H-uridine into RNA of 11-day-old embryos and causes elimination of a RNA species characteristic of that developmental stage.

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Author notes

  1. Th. Palayoor

    Present address: Cancer Research Institute, Tata Memorial Centre, Parel, 400071, Bombay, India

Authors and Affiliations

  1. Section de Biochimie Cellulaire, Départ. de Radiobiologie, Centre d'Etudes de l'Energie Nucléaire, C. E. N./S. C. K., Mol, Belgium

    Th. Palayoor

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  1. Th. Palayoor
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Additional information

Acknowledgment. The author is indebted to Prof. L. Ledoux and Dr. W. Baeyens for their help and cooperation in this work.

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Palayoor, T. Transcriptional effects of 5-bromo-2′-deoxyuridine in post-implantation mouse embryos. Experientia 33, 448–450 (1977). https://doi.org/10.1007/BF01922203

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  • DOI: https://doi.org/10.1007/BF01922203

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