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Effects of Ag+ on frog skin: Interactions with oxytocin, amiloride and ouabain

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Summary

Different biological effects of Ag+ (10−4 M) were found depending on its presence in the outer or the inner solution bathing the frog skin. A marked increase in the electrical conductance and an interference with the action of oxytocin and amiloride were found only when Ag+ was added to the outer solution. Results suggest that Ag+ affects several transport processes, in particular the permeability of the Na entry pathways.

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References

  1. P. F. Curran, Biochim. biophys. Acta288, 90 (1972).

    Article  CAS  PubMed  Google Scholar 

  2. K. T. G. Ferreira, Biochim. biophys. Acta203, 555 (1970).

    Article  CAS  PubMed  Google Scholar 

  3. L. N. Fleisher, T. Yorio and P. J. Bentley, Toxic. appl. Pharmac.33, 384 (1975).

    Article  CAS  Google Scholar 

  4. R. C. De Sousa, J. Marguerat and A. Grosso, Experientia29, 748 (1973).

    Article  Google Scholar 

  5. Y. Yorio and P. J. Bentley, Comp. gen. Pharmac.4, 167 (1973).

    Article  CAS  Google Scholar 

  6. J. Marguerat, Thesis, University of Geneva, Geneva (1975).

  7. J. Yonath and M. M. Civan, J. Memb. Biol.5, 366 (1971).

    Article  Google Scholar 

  8. R. C. De Sousa, J. Physiol.71, 5A (1975).

    Google Scholar 

  9. J. Marguerat and R. C. De Sousa, Experientia31, 73 (1975).

    Article  CAS  PubMed  Google Scholar 

  10. J. H. Li, unpublished results.

  11. A. W. Cuthbert, Molec. Pharmac.10, 892 (1974).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Departments of Physiology and Medicine, School of Medicine, University of Geneva, 20, rue de l'Ecole de Médecine, 1211, Genève 4, Switzerland

    J. H. Li & R. C. de Sousa

Authors
  1. J. H. Li
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  2. R. C. de Sousa
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Additional information

This work was supported by the Swiss National Science Foundation, grant No. 1.300.73. We thank Mrs A. Cergneux for skilful secretarial assistance.

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Li, J.H., de Sousa, R.C. Effects of Ag+ on frog skin: Interactions with oxytocin, amiloride and ouabain. Experientia 33, 433–436 (1977). https://doi.org/10.1007/BF01922195

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  • DOI: https://doi.org/10.1007/BF01922195

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