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Histamine formation by ruminal fluid from cattle in vitro

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Summary

Net histamine formation in ruminal fluid is shown to be the result of histidine decarboxylation and histamine deamination. Addition of 4.7 mM histidine increased the rate of net histamine synthesis by a factor of 20 compared to normal. Histamine production sharply decreases at pH values below the physiological range.

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Authors and Affiliations

  1. Veterinärpharmakologisches Institut der Universität Bern, Länggassstrasse 124, CH-3000, Bern, Switzerland

    A. Wicki & H. J. Schatzmann

Authors
  1. A. Wicki
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  2. H. J. Schatzmann
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Wicki, A., Schatzmann, H.J. Histamine formation by ruminal fluid from cattle in vitro. Experientia 33, 422–423 (1977). https://doi.org/10.1007/BF01922188

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  • DOI: https://doi.org/10.1007/BF01922188

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