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Selective toxicity of amanitin-albumin conjugates for macrophages

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Riassunto

Viene descritta la particolare sensibilità dei macrofagi al coniugato amanitina-albumina. È inoltre prospettata e discussa la possibile attività antineoplastica di coniugati dell'albumina con sostanze inibenti la mitosi o la sintesi del DNA.

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  23. Acknowledgments. We thank ProfessorTh. Wieland for a generous gift of α- and β-amanitin. The excellent technical assistance of MrL. Franchi and MrA. Mattioli is acknowledged. This investigation was supported by grants from C.N.R. (Rome) and Pallotti's legacy for Cancer Research.

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Authors and Affiliations

  1. Istituto di Patologia Generale dell' Università, Via San Giacomo 14, I-40126, Bologna, Italy

    L. Fiume & G. Barbanti-Brodano

  2. Istituto di Microbiologia dell' Università, Via San Giacomo 12, I-40126, Bologna, Italy

    L. Fiume & G. Barbanti-Brodano

Authors
  1. L. Fiume
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  2. G. Barbanti-Brodano
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Fiume, L., Barbanti-Brodano, G. Selective toxicity of amanitin-albumin conjugates for macrophages. Experientia 30, 76–77 (1974). https://doi.org/10.1007/BF01921609

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