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Differentiation of cultured muscle in the presence ofα-bungarotoxin

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Résumé

Nous avons étudié le rôle du récepteur cholinergique dans la différentiation du muscle de squelette en culture. En présence continuelle de la α-bungarotoxine, les cellules n'ont pas réagi à l'acétylcholine, mais la myogénèse et l'acétylcholinestérase ont été normales. Nous concluons que la myogénèse en culture ne dépend pas de la présence des récepteurs cholinergiques fonctionnels.

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Authors and Affiliations

  1. Department of Physiology and Pharmacology, University of Strathclyde, George Street, G1 1XW, Glasgow, UK

    A. L. Harvey & W. F. Dryden

Authors
  1. A. L. Harvey
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  2. W. F. Dryden
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Additional information

We gratefully acknowledge financial support from the Medical Research Council (to A.L.H.) and from the Scottish Home and Health Department. (to. W.F.D.). We thank Mrs.B. Hamilton for skilled technical assistance.

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Harvey, A.L., Dryden, W.F. Differentiation of cultured muscle in the presence ofα-bungarotoxin. Experientia 30, 613–615 (1974). https://doi.org/10.1007/BF01921502

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