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Collagenolytic enzymes and acid-proteinase activity in granuloma tissue

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Zusammenfassung

Die Kathepsin D-Aktivität des kollagenolytischen Kathepsins und der Pz-Peptidase wurden während der Bildung des mittels s.c. Injektion von Terpentinol hervorgerufenen Granuloms bei Ratten verfolgt. Die Kathepsin D-Aktivität erreichte am 10. Tag ihren Höhepunkt, diejenige des kollagenolytischen Kathepsins und der Pz-Peptidase erst am 14. Tag. In dieser Phase ist die Kollagenkonzentration herabgesetzt, während sich eine ausgeprägte Resorption des Granuloms zeigt.

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Authors and Affiliations

  1. Research Institute of Rheumatic Diseases, 92101, Piešťany, Czechoslovakia

    M. Stančíková & K. Trnavský

Authors
  1. M. Stančíková
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  2. K. Trnavský
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Stančíková, M., Trnavský, K. Collagenolytic enzymes and acid-proteinase activity in granuloma tissue. Experientia 30, 594–595 (1974). https://doi.org/10.1007/BF01921491

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