Zusammenfassung
Die durch Rose Bengal sensibilisierte Photooxydation des Hemopyrrols in Methanol ergab 3-Äthyl-5-methoxy-4,5-dimethyl-3-pyrrolin-2-on, 3-Äthyl-3-hydroxy-4,5-dimethyl-4-pyrrolin-2-on und 3-Äthyl-5-hydroxy-4,5-dimethyl-3-pyrrolin-2-on.
Literatur
D. G. Irvine andL. Wetterberg, Lancet2, 1201 (1972).
D. A. Lightner andD. C. Crandall, Experientia29, 262 (1973).
L. Wetterberg, Uppsala J. med. Sci.78, 78 (1973).
D. G. Irvine, W. Bayne, H. Miyashita andJ. R. Majer, Nature Lond.244, 811 (1969).
Hemopyrrole was prepared by the tedious procedure ofFischer, H. Fischer andH. Orth,Die Chemie des Pyrrols (Academische Verlagsgesellschaft mbH, Leipzig 1934), vol. 1, p. 51.
Westinghouse tungsten-halogen quartz lamp, 120V, 500W, No. 500 Q/CL run at 80V.
All mass spectra were determined on a Varian MAT 311 mass spectrometer, all NMR-spectra were run on a Varian XL-100 instrument; IR-spectra were recorded using a Perkin-Elmer model 457 spectrometer.
We wish to thank Dr.Z. Petryka, Northwestern Hospital, Minneapolis, Minn. for a generous sample of ethylmethylmaleimide.
G. B. Quistad andD. A. Lightner, Tetrahedron Lett.1971, 4417.
D. A. Lightner andL. K. Low, Chem. Commun.1972, 625.
K. Gollnick andG. O. Schenck,1,4-Cycloaddition Reactions, (Ed.J. Hamer; Academic Press, New York 1967).
D. A. Lightner, andL. K. Low, J. heterocycl. Chem.9, 167 (1972).
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The authors wish to thank the National Science Foundation (GP-35699X) and the National Institute of Child Health and Human Development (HD-07358) for generous support of this work. We thank Mr.Jordan Hodge for determining all mass spectra reported in this work.
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Lightner, D.A., Norris, R.D., Kirk, D.I. et al. The dye-sensitized photooxygenation of hemopyrrole. Experientia 30, 587–588 (1974). https://doi.org/10.1007/BF01921487
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DOI: https://doi.org/10.1007/BF01921487