Experientia

, Volume 32, Issue 4, pp 497–498 | Cite as

Distribution of polychlorinated biphenyls: Structural requirements for accumulation in the mouse bronchial mucosa

  • I. Brandt
  • A. Bergman
  • C. A. Wachtmeister
Specialia

Summary

Autoradiography showed that labelled polychlorinated biphenyls with chlorine in positions 2, 41, 5 and hydrogen in positions 3, 31, 6, 61 in the molecule are accumulated in the mouse bronchial mucosa. Further testing of this observation showed that 2, 21, 4, 51-tetrachlorbiphenyl-14C, but not biphenyl-14C, was taken up in the bronchi of mice.

Keywords

Hydrogen Chlorine Biphenyl Structural Requirement Bronchial Mucosa 

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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • I. Brandt
    • 1
    • 2
  • A. Bergman
    • 1
    • 2
  • C. A. Wachtmeister
    • 1
    • 2
  1. 1.Department of ToxicologyUniversity of Uppsala, Biomedical CenterUppsala(Sweden)
  2. 2.Section of Organic Chemistry, Environmental Toxicology Unit, Wallenberg LaboratoryUniversity of StockholmStockholm 50(Sweden)

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