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The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide

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Summary

The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a rectilinear one with up to 70% reduction in activity with the administration of 25% heavy water.

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Hayes, C.J., Palmer, J.D. The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide. Experientia 32, 469–470 (1976). https://doi.org/10.1007/BF01920801

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