Abstract
Serotonin (5-hydroxytryptamine, 5-HT) stimulates spawning in the zebra mussel (Dressena polymorpha), a macrofouling European bivalve that has recently invaded North America. To develop methods of controlling zebra mussel spawning, two vertebrate serotonin antagonists, methiothepin and metergoline, known to bind with high affinity to snail 5-HT receptors, were tested for their ability to block 5-HT-induced spawning in zebra mussels. Methiothepin inhibited 5-HT-induced spawning at concentrations as low as 10−6 M. Metergoline (10−4 M) inhibited 5-HT-induced spawning; however, at lower concentrations (10−8 to 10−5 M), metergoline by itself significantly induced spawning in male, but not female zebra mussels. Metergoline (10−5 M)-induced male spawning was inhibited by 10−5 M methiothepin. Thus, methiothepin is the most effective inhibitor and metergoline the most powerful inducer of spawning yet tested in zebra mussels.
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Literatur
Ram, J. L., Fong, P. P., Croll, R. P., Nichols, S. J. and Wall, D. M., Invert. Repord. Dev.22 (1992) 77.
Karnaukhov, V. N., and Karnaukhov, A. V. in: Zebra Mussels: Biology, Impacts, and Control., p. 729. Eds T. F. Nalepa and D. W. Schloesser, Lewis Publishers, Boca Raton, Florida 1993.
Blodgett, K. D., Thiel, P. A., Miller, A. C., and Sparks, R. E., Proc. 2nd Int. Zebra Mussel Res. Conf., Rochester, New York (1991) 40.
Lange, C. L., and Cap, R. K., Proc. 2nd Int. Zebra Mussel Res. Conf., Rochester, New York (1991) 28.
Sastry, A. N., in: Reproduction of Marine Invertebrates, vol. 5, p. 113. Eds. A. C. Giese and J. S. Pearse. Academic Press, New York 1979.
Kasyanov, V. L., Biologiya Morya-Marine Biology3 (1991) 100.
Paulet, Y.-M., and Boucher, J., Invert. Reprod. Dev.19, (1991) 61.
Orton, J. H., J. mar. biol. Ass. UK12 (1920) 339.
Thorson, G., Meddr Kommn Danm. Fisk-og Havunders., Ser. Plankton 4 (1946) 1.
Borcherding, J., Oecologia87, (1991) 208.
Braley, R. D., Coral Reefs3 (1984) 221.
Heslinga, G. A., Perron, F. E., and Orak, O., Aquaculture39 (1984) 197.
Starr, M., Himmelman, J. H., and Therriault, J.-C., Science247 (1990) 1071.
Matsutani, T., and Nomura, T., Mar. Biol. Lett.3 (1982) 353.
Gibbons, M. C., and Castagna, M., Aquaculture40 (1984) 189.
Crawford, C. M., Nash, W. J., and Lucas, J. S., Aquaculture58 (1986) 281.
Belda, C. A., and del Norte, A. G. C., Aquaculture72 (1988) 173.
Velez, A., Alifa, E., and Azuaje, O., Aquaculture84 (1990) 307.
Lefort, Y., C. r. hebd. Séanc. Acad. Sci., Paris. Ser III-Sci. Vie314 (1992) 607.
Ram, J. L., Crawford, G. W., Walker, J. U., Mojares, J. J., Patel, N., Fong, P. P., and Kyozuka, K., J. exp. Zool.265 (1993) 587.
Matsutani, T., in: Advances in Invertebrate Reproduction5, p. 231. Eds M. Hoshi and O. Yamashita, Elsevier Science Publishers B. V. (Biomedical Division), Amsterdam 1990.
Fong, P. P., Wall, D. M., and Ram, J. L., J. exp. Zool.267 (1993) 475.
Sugamori, K. S., Sunahara, R. K., Guan, H., Bulloch, A. G., Tensen, C. P., Seeman, P., Niznik, H. B., and Van Tol, H. H. M., Proc. natl Acad. Sci. USA90 (1993) 11.
Fiorica-Howells, E., Wade, P. R., and Gershon, M. D., Synapse13 (1993) 333.
Aulakh, C. S., Hill, J. L., and Murphy, D. L., J. Pharmac. exp. Ther.263 (1992) 588.
Sokol, R. R., and Rohlf, F. J., Biometry, 2nd edn W. H. Freeman Co., San Francisco 1981.
Bradley, P. B., Engel, G., Feniuk, W., Fozard, J. R., Humphrey, P. P., Middlemiss, D. N., Mylecharane, E. J., Richardson, B. P., and Saxena, P. R., Neuropharmacology25 (1986) 563.
Peroutka, S. J., Trends Neurosci.11 (1988) 496.
Ram, J. L., and Nichols, S. J., in: Zebra Mussels, Biology, Impacts, and Control, p. 307. Eds. T. F. Nalepa and D. W. Schloesser. Lewis Publishers, CRC Press, Boca Raton, Florida 1993.
Krantic, S., Dube, F., Quiron, R., and Guerrier, P., Devl Biol.146 (1991) 491.
Krantic, S., Guerrier, P., and Dube, F., J. biol. Chem.268 (1993) 7983.
Krantic, S., Dube, F., and Guerrier, P., Gen. comp. Endocr.90 (1993) 125.
Kyozuka, K., Fong, P. P., Abdel Ghani, H., and Ram, J. L., Proc. 3rd Int. Zebra Mussel Conf., Toronto, Ontario 1993.
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fong, P.P., ducan, J. & Ram, J.L. Inhibition and sex specific induction of spawning by serotonergic ligands in the zebra musselDreissena polymorpha (Pallas). Experientia 50, 506–509 (1994). https://doi.org/10.1007/BF01920759
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DOI: https://doi.org/10.1007/BF01920759