, Volume 35, Issue 2, pp 247–248 | Cite as

Dose-effects of 8-methoxypsoralen and long wave UV-light in 3T3 cells: evaluation of a phototoxic index

  • J. Pohl
  • E. Christophers


3T3 cells were cultured until confluency and treated with various doses of 8-methoxypsoralen followed by long wave UV light irradiation. The inhibition of3H-thymidine incorporation was dose-dependent for both, psoralen and light. A phototoxic index (PTI) was established demonstrating that a constant correlation between psoralen and UVA light exists for the photoinactivation in living cells.


Living Cell Light Irradiation Psoralen Constant Correlation 
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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • J. Pohl
    • 1
  • E. Christophers
    • 1
  1. 1.Dept. of DermatologyUniversity of KielKiel(Federal Republic of Germany)

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