Skip to main content

Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea-pigs,Cavia porcellus

Experientia volume 35, pages 231–233 (1979)Cite this article

Summary

The treatment of pigmented guinea-pigs with melatonin aggregates pigmented cells in the retinal pigment epithelium and choroid of the eye. This suggests that melatonin may regulate eye pigmentation in vertebrates.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

References

  1. A. B. Lerner, J. D. Case, Y. Takahashi, T. H. Lee and W. Mori, J. Am. Chem. Soc.80, 2587 (1958).

    Article  Google Scholar 

  2. A. B. Lerner, J. D. Case and R. V. Heinzelman, J. Am. Chem. Soc.81, 6084 (1959).

    Article  Google Scholar 

  3. R. J. Wurtman, J. Axelrod and D. E. Kelly, The Pineal. Academic Press, New York 1968.

    Google Scholar 

  4. C. L. Ralph, Am. Zool.16, 35 (1976).

    Google Scholar 

  5. R. W. Pelham, C. L. Ralph and I. M. Campbell, Biochem. biophys. Res. Commun.46, 1236 (1972).

    Article  PubMed  Google Scholar 

  6. R. W. Pelham, Endocrinology96, 543 (1975).

    PubMed  Google Scholar 

  7. S. F. Pang and C. L. Ralph, J. exp. Zool.193, 275 (1975).

    Article  PubMed  Google Scholar 

  8. J. Arendt, L. Pannier and P. C. Sizonenko, J. clin. Endocr. Metab.40, 347 (1975).

    PubMed  Google Scholar 

  9. G. M. Vaughan, R. W. Pelham, S. F. Pang, L. L. Laughlin, K. M. Wilson, K. L. Sandock, M. K. Vaughan, S. H. Koslow and R. J. Reiter, J. clin. Endocr. Metab.42, 752 (1976).

    PubMed  Google Scholar 

  10. F. W. Turek, C. Desjardins and M. Menaker, Science190, 280 (1975); F. W. Turek, C. Desjardins and M. Menaker, Proc. Soc. exp. Biol. Med.151, 502 (1976).

    PubMed  Google Scholar 

  11. J. E. Martin and D. C. Klein, Science191, 301 (1976).

    PubMed  Google Scholar 

  12. L. C. Ellis, Am. Zool.16, 67 (1976).

    Google Scholar 

  13. W. B. Quay, Pineal Chemistry, Thomas, Springfield 1974.

    Google Scholar 

  14. S. F. Pang, C. L. Ralph and D. P. Reilly, Gen. Comp. Endocr.22, 499 (1974).

    Article  PubMed  Google Scholar 

  15. S. F. Pang, G. M. Brown, L. J. Grota, J. W. Chambers and R. L. Rodman, Neuroendocrinology23, 1 (1977).

    PubMed  Google Scholar 

  16. G. A. Bubenik, G. M. Brown, I. Uhlir and L. J. Grota, Brain Res.81, 233 (1974).

    Article  PubMed  Google Scholar 

  17. G. A. Bubenik, G. M. Brown and L. J. Grota, Brain Res.118, 417 (1976a); G. A. Bubenik, G. M. Brown and L. J. Grota, J. Histochem. Cytochem.24, 1173 (1976b); G. A. Bubenik, G. M. Brown and L. J. Grota, Experientia32, 579 (1976c).

    Article  PubMed  Google Scholar 

  18. A. B. Lerner and J. D. Case, J. invest. Derm.32, 211 (1959).

    PubMed  Google Scholar 

  19. W. B. Quay and J. T. Bagnara, Archs Inst. Pharmacodyn. Ther.150, 137 (1964).

    Google Scholar 

  20. C. L. Ralph and H. J. Lynch, Gen. Comp. Endocr.15, 334 (1970).

    Article  PubMed  Google Scholar 

  21. R. M. Wright and A. B. Lerner, Endocrinology66, 599 (1960).

    PubMed  Google Scholar 

  22. R. S. Snell, J. invest. Derm.44, 273 (1965).

    PubMed  Google Scholar 

  23. J. S. McGuire and H. Moller, Nature298, 493 (1965).

    Google Scholar 

  24. D. Mull and C. L. Ralph, Am. Zool.12, 674 (1972).

    Google Scholar 

  25. W. B. Quay, Life Sci.4, 983 (1965).

    Article  PubMed  Google Scholar 

  26. S. F. Pang, D. T. Yew and H. W. Tsui, Neurosci. Lett., in press (1978).

Download references

Author information

Affiliations

  1. Department of Physiology and Department of Anatomy, Faculty of Medicine, University of Hong Kong, (Hong Kong)

    S. F. Pang & D. T. Yew

Authors
  1. S. F. Pang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. T. Yew
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

We thank Mr M.K. Yip, Mr C.Y. Wat and Miss P. Yip for assistance and Prof. A. Hsieh and Prof. J. Widdicombe for reading the manuscript.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Pang, S.F., Yew, D.T. Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea-pigs,Cavia porcellus . Experientia 35, 231–233 (1979). https://doi.org/10.1007/BF01920634

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01920634

Keywords

  • Melatonin
  • Retinal Pigment Epithelium
  • Retinal Pigment
  • Pigment Epithelium
  • Pigment Aggregation