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Effects of arsenite and oxamate on the in vitro functional activity of estrogen-dominated rat uterine horns

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Summary

Arsenite but not oxamate produce in vitro a distinct depression of estrogen-dominated uterine motility, both in the absence of substrate as well as in the presence of exogenous glucose or lactate. The addition of oxamate to preparations suspended in a medium with lactate as the sole external substrate ameliorates the depression of uterine motility elicited by arsenite.

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This work has been supported by grants 6638 and 6294 from the Consejo Nacional de Investigaciones Cientificas y Técnicas de la República Argentina.

Senior Investigator of the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina.

Junior Investigator of the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina.

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Gimeno, A.L., Goldraij, A. & Gimeno, M.F. Effects of arsenite and oxamate on the in vitro functional activity of estrogen-dominated rat uterine horns. Experientia 35, 221–222 (1979). https://doi.org/10.1007/BF01920628

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  • DOI: https://doi.org/10.1007/BF01920628

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