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Zinc deficiency and lung converting enzyme activity in rats

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Summary

Angiotensin converting enzyme activity was found to be significantly decreased in the isolated perfused lung from zinc-deficient rats when compared with that of controls. Addition of zinc ion to the superfusion medium did not cause a recovery in this decreased activity of the enzyme. It is postulated that zinc deficiency probably produces a structural change in the lung angiotensin converting enzyme.

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This work is supported by a grant from Turkish Scientific and Technical Research Council (TAG-350).

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Ercan, Z.S., Öner, G., Türker, R.K. et al. Zinc deficiency and lung converting enzyme activity in rats. Experientia 35, 215–216 (1979). https://doi.org/10.1007/BF01920624

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