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Chromosome aberrations in in vitro irradiated lymphocytes from human cord blood

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Summary

An in vitro dose effect curve of dicentric chromosome aberrations in human cord blood lymphocytes has been obtained for 250-kV X-rays. This is compared with a curve prepared in an identical manner using blood from adults. The comparison shows a marginally higher dicentric yield in blood of newborns at doses above about 250 rads.

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Authors and Affiliations

  1. National Radiological Protection Board, Harwell, OX11 ORQ, Didcot, Oxon, England

    D. C. Lloyd & E. J. Reeder

Authors
  1. D. C. Lloyd
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  2. E. J. Reeder
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Additional information

Acknowledgment. We wish to thank Miss P. Orledge of the John Radcliffe Hospital, Oxford, for samples of cord blood, Mr M.J. Corp of the MRC Radiobiology Unit, Harwell, for irradiating the samples and Mr A.A. Edwards of NRPB, for help with statistics. The work was partly supported by Euratom Contract No. 171-76-1 BIO UK.

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Lloyd, D.C., Reeder, E.J. Chromosome aberrations in in vitro irradiated lymphocytes from human cord blood. Experientia 35, 176–177 (1979). https://doi.org/10.1007/BF01920597

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