Summary
Changes in realtive levels of cyclic AMP-dependent protein kinase (A-PK) and cyclic GMP-dependent protein kinase (G-PK) in prostates, epididymides and testes from guinea-pigs were examined at 3 different ages. During postnatal development, a decrease in the ratio of the 2 classes of protein kinases was seen in prostates, whereas increases of the ratios of the enzymes were found in epididymides and testes.
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J.F. Kuo and W.N. Kuo, Biochem. biophys. Res. Commun.55, 660 (1973).
N.D. Goldbert, R. O'Dea and M. Haddox, Adv. Cyclic Nucleotide Res.3, 155 (1973).
J.F. Kuo and P. Greengard, J. biol. Chem.245, 2493 (1970).
J.F. Kuo and P. Greengard, Proc. natl Acad. Sci. USA64, 1349 (1969).
J.F. Kuo, Proc. natl Acad. Sci. USA71, 4037 (1974).
J.F. Kuo, Proc. natl Acad. Sci. USA72, 2256 (1975).
M.M. Appleman, L. Birnbaumer and H.N. Torres, Arch. Biochem. Biophys.116, 39 (1966).
D.A. Walsh, C.D. Ashby, C. Gonzalez, D. Calkins, E.H. Fisher and E.G. Krebs, J. biol. Chem.245, 1977 (1971).
W.N. Kuo and J.F. Kuo, J. biol. Chem.251, 4283 (1976).
W.N. Kuo, unpublished.
C.W. Davis and J.F. Kuo, Biochim. biophys. Acta444, 554 (1976).
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Acknowledgments. This work was supported by grant RR-08199 from the National Institutes of Health, USA. The authors thank Dr J.F. Kuo, in whose laboratory part of this work was performed, for his great advice.
Undergraduate trainee of Minority Biomedical Support.
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Kuo, W.N., Williams, J.L. Ontogenetic changes in relative levels of cyclic AMP-dependent and cyclic GMP-dependent protein kinases in prostates, epididymides and testes from guinea-pigs. Experientia 35, 158–159 (1979). https://doi.org/10.1007/BF01920584
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DOI: https://doi.org/10.1007/BF01920584