Summary
Prevention by S-adenosyl-L-methionine (SAMe) of the bile flow reduction induced by ethynylestradiol (EE) is demonstrated by comparing the flow rate and the bile salt concentration of bile in EE-treated animals with that in animals given both EE and SAMe.
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References
T. A. J. Heikel and G. H. Lathe, Br. J. Pharmac.38, 593 (1970).
R. A. Davis and F. Kern, Gastroenterology70, 1130 (1976).
J. J. Gumucio and V. D. Valdivieso, Gastroenterology61, 339 (1971).
J. Fishman, J. clin. Endocr. Metab.23, 207 (1963).
P. Ball, H. P. Gelbke and R. Knuppen, J. clin. Endocr. Metab.40, 406 (1975).
R. Knuppen, O. Haupt and H. Breuer, Biochem. J.118, 9p (1970).
G. L. Cantoni, J. biol. Chem.204, 403 (1953).
G. L. Cantoni and J. Durell, J. biol. Chem.225, 1033 (1957).
P. Talalay, in: Methods of Biochemical Analysis, vol. 8, p. 119. Ed. D. Glick, Wiley & Sons Inc., New York 1960.
H. Kappus and H. M. Blot, Hormone Metab. Res.6, 333 (1974).
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SAMe was supplied by Bio Research Co., 20060 Liscate (Milano), Italy.
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Stramentinoli, G., Gualano, M. & Di Padova, C. Effect of S-adenosyl-L-methionine on ethynylestradiol-induced impairment of bile flow in female rats. Experientia 33, 1361–1362 (1977). https://doi.org/10.1007/BF01920182
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DOI: https://doi.org/10.1007/BF01920182