, Volume 33, Issue 10, pp 1346–1348 | Cite as

The relative sensitivity of pulmonary parenchymal cells to239plutonium dioxide

  • A. G. Heppleston
  • A. E. Young


Alpha particles inhaled by mice affect primarily type II epithelial cells, whereas interstitial mononuclears, alveolar macrophages and type I epithelium are much more resistant and apparently react secondarily. The cellular responses, qualitative and quantitative, exhibit a time-dose relationship.


Epithelial Cell Dioxide Cellular Response Alveolar Macrophage Parenchymal Cell 
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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • A. G. Heppleston
    • 1
  • A. E. Young
    • 1
  1. 1.University Department of PathologyRoyal Victoria InfirmaryNewcastle upon Tyne(England)

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