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Effect of pancreatic polypeptide on DNA-synthesis in the pancreas

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Summary

Bovine pancreatic polypeptide increases DNA-synthesis in the rat pancreas; no effect is observed in stomach (oxyntic area), duodenum or liver. BPP neither augments or inhibits the trophic action of cholecystokinin.

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Acknowledgment. Pure pancreatic polypeptide was donated by Dr. R. E. Chance (Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Ind, USA). G. R. Greenberg is supported by a Fellowship of the Medical Research Council of Canada.

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Greenberg, G.R., Mitznegg, P. & Bloom, S.R. Effect of pancreatic polypeptide on DNA-synthesis in the pancreas. Experientia 33, 1332–1333 (1977). https://doi.org/10.1007/BF01920164

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  • DOI: https://doi.org/10.1007/BF01920164

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