, Volume 33, Issue 10, pp 1331–1332 | Cite as

Effect of catecholamines on ADP aggregation of rat platelets in vivo

  • Maria Gabriella Doni
  • R. Aragno


The influence of catecholamines on the platelet count was studied in an in vivo experimental model obtained with cannulation of the carotid and of the femoral vein. The i.v. infusion of epinephrine and l-norepinephrine induces a low drop in the platelet count and also potentiate aggregation by ADP.


Experimental Model Platelet Count Epinephrine Catecholamine Femoral Vein 
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  1. 1.
    Z. Sinakos and J. P. Caen, Thromb. Diath, haemorrh.17, 99 (1969).Google Scholar
  2. 2.
    M. A. Packham and J. F. Mustard, Semin. Haematol.8, 30 (1971).Google Scholar
  3. 3.
    D. C. B. Mills, Symp. Zool. Soc. Lond.27, 99 (1970).Google Scholar
  4. 4.
    H. G. Ardlie, G. Glew and C. J. Schwartz, Nature, Lond.212, 415 (1966).Google Scholar
  5. 5.
    D. C. B. Mills and G. C. K. Roberts, J. Physiol., Lond.193, 443 (1967).Google Scholar
  6. 6.
    S. Bygdeman and O. Johnsen, Acta physiol. scand.75, 129 (1969).PubMedGoogle Scholar
  7. 7.
    G. Berry and J. W. Miller, Eur. J. Pharmac.28, 164 (1974).CrossRefGoogle Scholar
  8. 8.
    I. Kobayashi and M. Didisheim, Thromb. Diath. haemorrh.30, 178 (1973).PubMedGoogle Scholar
  9. 9.
    M. G. Doni and R. Aragno, Experientia31, 1224 (1975).PubMedGoogle Scholar
  10. 10.
    R. Aragno and M. G. Doni, Thromb. Res.9, 319 (1976).CrossRefPubMedGoogle Scholar
  11. 11.
    M. G. Doni, R. Aragno and P. Vassanelli, Thromb. Res.10, 539 (1977).CrossRefPubMedGoogle Scholar
  12. 12.
    D. G. McMillan, Nature, Lond.211, 140 (1966).Google Scholar
  13. 13.
    M. G. Doni, Experientia30, 550 (1974).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • Maria Gabriella Doni
    • 1
  • R. Aragno
    • 1
  1. 1.Institute of Human Physiology, Faculty of MedicineUniversity of PaduaPadova(Italy)

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