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Experientia

, Volume 33, Issue 10, pp 1280–1281 | Cite as

Effect of aldosterone and methylprednisolone on cardiac NaK-ATPase

  • C. Hegyvary
Specialia Chimica, Biochimica

Summary

Aldosterone (15 μg BID) and methylprednisolone (8 mg QD) administration to female guinea-pigs augmented both the total and the specific activity of NaK-ATPase but not the activity of adenylate cyclase in the cardiac sarcolemma. The rise in NaK-ATPase was due to increase in the number of enzyme molecules; catalytic activity and ouabain-sensitivity of individual molecules did not change.

Keywords

Enzyme Catalytic Activity Aldosterone Methylprednisolone Adenylate Cyclase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • C. Hegyvary
    • 1
  1. 1.Departments of Medicine and PhysiologyRush University Medical CollegeChicagoUSA

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