, Volume 33, Issue 10, pp 1280–1281 | Cite as

Effect of aldosterone and methylprednisolone on cardiac NaK-ATPase

  • C. Hegyvary
Specialia Chimica, Biochimica


Aldosterone (15 μg BID) and methylprednisolone (8 mg QD) administration to female guinea-pigs augmented both the total and the specific activity of NaK-ATPase but not the activity of adenylate cyclase in the cardiac sarcolemma. The rise in NaK-ATPase was due to increase in the number of enzyme molecules; catalytic activity and ouabain-sensitivity of individual molecules did not change.


Enzyme Catalytic Activity Aldosterone Methylprednisolone Adenylate Cyclase 
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Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • C. Hegyvary
    • 1
  1. 1.Departments of Medicine and PhysiologyRush University Medical CollegeChicagoUSA

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