, Volume 32, Issue 6, pp 744–746 | Cite as

Teratogenic effect of tolbutamide on the development of the sea urchin embryo (Paracentrotus lividus lamarck)

  • B. E. Hagström
  • S. Lönning


The hypoglycemic agent tolbutamide was tested for its action on the cleavage and differentiation of the sea urchin embryo. Tolbutamide effects a strong selective action on the endoderm which becomes suppressed.


Tolbutamide Selective Action Teratogenic Effect Paracentrotus Lividus 
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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • B. E. Hagström
    • 1
    • 2
  • S. Lönning
    • 1
    • 2
  1. 1.KABI Research DepartmentStockholm 30(Sweden)
  2. 2.Institute of Biology and GeologyUniversity of TromsöTromsöNorway

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