, Volume 32, Issue 6, pp 691–693 | Cite as

Abnormally soluble collagen produced in fibroblasts cultures

  • G. Francis
  • Patricia V. Donnelly
  • N. di Ferrante


Abnormally soluble collagen is synthesized in vitro not only by skin fibroblasts of Marfan patients but also by those of patients with Ehlers-Danlos type V and cutis laxa. The excessive solubility of collagen is corrected by the addition to the culture medium of a synthetic flavonoid, (+)-catechin.


Collagen Flavonoid Catechin Type Versus Skin Fibroblast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag 1976

Authors and Affiliations

  • G. Francis
    • 1
  • Patricia V. Donnelly
    • 1
  • N. di Ferrante
    • 1
  1. 1.Laboratories of Connective Tissue Research, Department of BiochemistryBaylor College of MedicineHoustonUSA

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