Advertisement

Experientia

, Volume 33, Issue 11, pp 1493–1495 | Cite as

Ultrastructural changes in dog thyroid follicular cells elicit by concanavalin A in vitro

  • J. A. Fernandez-Pol
  • J. P. Binette
  • M. T. Hays
Pharmacologica

Summary

Dog thyroid follicular cells exposed to concanavalin A (Con A) in vitro showed changes in cell shape, induction of colloid droplets and alterations in the distribution of microvilli. Cells exposed to Con A plus suboptimal concentrations of TSH (thyroid stimulating hormone) showed pseudopods and their cytoplasm was virtually occupied with colloid droplets. This findings suggest that Con A potentiated pseudopod and colloid droplet formation induced by TSH.

Keywords

Cell Shape Thyroid Stimulate Hormone Stimulate Hormone Concanavalin Ultrastructural Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 2.
    P. Cuatrecasas and G. P. E. Tell, Proc. nat. Acad. Sci. USA70, 485 (1973).PubMedGoogle Scholar
  2. 3.
    M. P. Czech and W. S. Lynn, Biochem. biophys. Acta297, 368 (1973).PubMedGoogle Scholar
  3. 4.
    J. Kubota and H. Kanatani, Science187, 654 (1975).PubMedGoogle Scholar
  4. 5.
    J. A. Fernandez-Pol, M. T. Hays and J. P. Binette, Exp. molec. Path. USA, in press (1977).Google Scholar
  5. 6.
    B. Storrie, J. cell. Biol.59, 471 (1973).PubMedGoogle Scholar
  6. 7.
    M. C. Willingham, Int. Rev. Cytol.44, 319 (1976).PubMedGoogle Scholar

Copyright information

© Experientia 1977

Authors and Affiliations

  • J. A. Fernandez-Pol
    • 1
    • 2
  • J. P. Binette
    • 1
    • 2
  • M. T. Hays
    • 1
    • 2
  1. 1.Laboratory of Electron MicroscopyVeterans Administration HospitalBuffalo
  2. 2.Department of Medicine and Nuclear Medicine of the State University of New York at BuffaloBuffaloUSA

Personalised recommendations