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Mechanical responses of the isolated cervix of the day-22 pregnant rat to field stimulation

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Summary

Field stimulation of isolated, spirally-cut cervix from day-22 pregnant rats produced contractions which could be inhibited by tetrodotoxin or hyoscine and potentiated by propranolol. The rat cervix would appear to receive both cholinergic and noradrenergic innervations whose transmitters activate muscarinic cholinoceptors and β-adrenoceptors respectively.

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References

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Authors and Affiliations

  1. Departments of Pharmacology, Materia Medica and Therapeutics, and Child Health, Medical School, University of Manchester, M13 9PT, Manchester, (England)

    M. Hollingsworth & Catherine N. M. Isherwood

Authors
  1. M. Hollingsworth
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  2. Catherine N. M. Isherwood
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Additional information

We thank the Lalor Foundation, USA, for financial support.

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Hollingsworth, M., Isherwood, C.N.M. Mechanical responses of the isolated cervix of the day-22 pregnant rat to field stimulation. Experientia 35, 72–73 (1979). https://doi.org/10.1007/BF01917884

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  • DOI: https://doi.org/10.1007/BF01917884

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