Summary
Some di- and tripeptides containing homoleucine (2-amino-4-methylhexanoic acid) have been synthetized. These compounds have been submitted to biological tests on insects for their hormonal activity in comparison with the known tripeptide pivaloyl-alanyl-p-aminobenzoic acid ethyl ester. Only 2 of them (3 and 4) caused morphological changes on larvae ofPyrrhocoris apterus.
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This work has received financial support from the Consiglio Nazionale delle Ricerche.
The biological assays were done in the Research Center of Montedison S.p.A. (Linate, Milano); the collaboration of Dr G. Michièli is gratefully acknowledged.
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Bernasconi, S., Corbella, A., Ferrari, M. et al. Di- and tripeptides containing homoleucine: synthesis and biological assays on insects. Experientia 35, 11–13 (1979). https://doi.org/10.1007/BF01917843
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DOI: https://doi.org/10.1007/BF01917843