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The use of microcalorimetry in studies of mammalian cells

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Abstract

Recent developments in instrumentation and working procedure in microcalorimetry have led to an increased interest in the direct measurements of heat production rates of living cells. Specific problems connected in particular with work on mammalian cells are briefly discussed and a system of microcalorimeters suitable for work on such cells is described. A few examples of its use in studies ofT-lymphoma cells are briefly discussed.

Zusammenfassung

In letzter Zeit führte die Entwicklung von Geräten und Arbeitsvorschriften in der Mikrokalorimetrie zu erhöhtem Interesse an direkten Messungen der Wärmeproduktionsgeschwindigkeit von lebenden Zellen. Spezifische Probleme im Zusammenhang mit der Arbeit an Säugetierzellen werden kurz dargelegt und ein zur Arbeit an solchen Zellen geeignetes Mikrokalorimetriesystem beschrieben. Einige Anwendungsbeispiele werden and Hand der Untersuchungen vonT-Lymphozyten kurz beschrieben.

Резуме

Недавние достижения аппаратурных и экспериментальных р азработок в микрокал ориметрии, привело к увеличению интереса в области из мерений скоростей теплообра зования в живых клетках. Кратк о обсуждены специфич еские проблемы, касающиеся работы с клетками млекопытающих, и опис ана система микрокал ориметров, приемлемых для работ ы с такими клетками. Кратко обсу ждено несколько прим еров использования таких микрокалориметров при изученииT-лимфоц итных клеток.

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References

  1. A. E. Beezer (ed), Biological Microcalorimetry, Academic Press, London 1980.

    Google Scholar 

  2. A. James (ed), Thermal and Energetic Studies of Cellular Biological Systems, Wright, Bristol 1987.

    Google Scholar 

  3. I. Wadsö in Biochemical Thermodynamics (M. N. Jones, ed), Elsevier, in press.

  4. I. Wadsö in reference 2.

    Google Scholar 

  5. J. Suurkuusk and I. Wadsö, Chem. Scripta, 20 (1982) 155.

    Google Scholar 

  6. M. Görman Nordmark, J. Laynez, A. Schön, J. Suurkuusk and I. Wadsö, J. Biochem. Biophys. Meth., 10 (1984) 198.

    Google Scholar 

  7. A. Schön and I. Wadsö, J. Biochem. Biophys. Meth., 13 (1986) 135.

    Article  PubMed  Google Scholar 

  8. A. Schön and I. Wadsö, Cytobios 48 (1987) 195.

    Google Scholar 

  9. C. A. K. Borrebaeck and A. Schön, Cancer Research, 47 (1987) 4345.

    PubMed  Google Scholar 

  10. A. Schön and I. Wadsö, unpublished results.

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Authors and Affiliations

  1. Division of Thermochemistry, Chemical Center, University of Lund, Box 124, S-221 00, Lund, Sweden

    A. Schön & I. Wadsö

Authors
  1. A. Schön
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  2. I. Wadsö
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Schön, A., Wadsö, I. The use of microcalorimetry in studies of mammalian cells. Journal of Thermal Analysis 33, 47–54 (1988). https://doi.org/10.1007/BF01914583

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  • DOI: https://doi.org/10.1007/BF01914583

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