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Role of muscular disuse in the genesis of fibrillation in denervated muscle

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Nei muscoli soleo-gastrocnemio di ratto la denervazione ha determinato insorgenza della fibrillazione dopo 60–66 h. Se eseguita dopo qualche giorno di disuso muscolare (conseguente a tenotomia, sezione del midollo spinale, immobilizzazione dell'arto) la denervazione ha determinato insorgenza della fibrillazione molto più precocemente, con un intervallo minimo di 24 h. Viene suggerito che nella genesi della fibrillazione dopo denervazione, il disuso muscolare abbia un ruolo importante.

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Authors and Affiliations

  1. Istituto di Fisiologia umana dell' Università di Trieste, Vid Alfonso Valerio, 34, I-34127, Trieste, Italy

    M. Midrio, F. Bouquet, M. Durighello & T. Princi

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  1. M. Midrio
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  2. F. Bouquet
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  3. M. Durighello
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  4. T. Princi
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Midrio, M., Bouquet, F., Durighello, M. et al. Role of muscular disuse in the genesis of fibrillation in denervated muscle. Experientia 29, 58–59 (1973). https://doi.org/10.1007/BF01913250

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