Advertisement

Basic Research in Cardiology

, Volume 76, Issue 5, pp 545–549 | Cite as

Coronary blood flow and hemodynamic effects of beta-adrenoceptor activation and beta-blockade in the baboon

  • C. Rosendorff
  • G. G. Rogers
  • C. J. Shimell
  • Anne Coull
  • L. Bomzon
Original Contributions
  • 18 Downloads

Key words

coronary myocardial haemodynamics β-adrenoreceptor β-blocker sotalol baboon 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Antilla, M., M. Arstila, M. Pfeffer, R. Tikkanen, V. Vallinkoski, H. Sundquist: Human Pharmacokinetics of sotalol. Acta Pharmacol. Toxicol.39, 118–128 (1976).Google Scholar
  2. Berne, R. M.: The coronary circulation. In: The Mammalian Myocardium, ed. by G. A. Langer and A. J. Brady, pp. 251–281, John Wiley and Sons, New York 1974).Google Scholar
  3. Brown, H. C., A. G. Carruthers, J. G. Kelly, D. G. McDevitt, R. G. Shanks: Observations on the efficacy and pharmacokinetics of sotalol after oral administration. Europ. J. Clin. Pharmacol.9, 367–372 (1976).Google Scholar
  4. Ekstrom-Jodal, B., E. Haggendal, R. Malmberg, N. Svedmyr: The effect of adrenergic β-receptor blockade on coronary circulation in man during work. Acta Med. Scand.191, 245–248 (1972).PubMedGoogle Scholar
  5. Lawrie, T. D. V., I. Hutton, A. R. Lorimer, S. Hills: Haemodynamic effects of sotalol. In: Advances in Beta-Adrenergic Blocking Therapy, Vol. 1-Pharmacology of Sotalol, ed. by A. G. Snart, pp. 35–40, Excerpta Medica (London 1974).Google Scholar
  6. Lewis, C. M., A. J. Brink: Beta adrenergic blockade. Haemodynamics and myocardial energy metabolism in patients with ischaemic heart disease. Amer. J. Cardiol.21, 846–859 (1968).PubMedGoogle Scholar
  7. Parratt, J. R.: Blockade of sympathetic beta-receptors in the myocardial circulation. Brit. J. Pharmacol.24, 601–611 (1965).Google Scholar
  8. Reale, A., A. Nigri, P. A. Gioffre, M. Motolese: Effect upon myocardial blood flow in man of beta blocking agents isosorbide dinitrate, dipyridamole and their combination, Postgrad. Med. J.46 (Suppl.), 60–66 (1970).Google Scholar
  9. Rivier, J. L., E. Nissiotis, M. Jaeger: Comparison of immediate haemodynamic effects of three beta-adrenergic blocking agents. Postgrad. Med. J.46 (Suppl), 44–49 (1970).PubMedGoogle Scholar
  10. Shanks, R. G., H. C. Brown, S. G. Carruthers, J. G. Kelly: Clinical pharmacology of sotalol. In: Advances in Beta-Adrenergic Blocking Therapy, Vol. 1-Pharmacology of Sotalol, ed. by A. G. Snart, pp. 23–24, Excerpta Medica (London 1974).Google Scholar
  11. Stein, P. D., H. L. Brooks, J. L. Matson, J. W. Hyland: Effects of beta-adrenergic blockade of coronary blood flow. Cardiovasc. Res.2, 63–67 (1968).PubMedGoogle Scholar

Copyright information

© Dr. Dietrich Steinkopff Verlag 1981

Authors and Affiliations

  • C. Rosendorff
    • 1
  • G. G. Rogers
    • 1
  • C. J. Shimell
    • 1
  • Anne Coull
    • 1
  • L. Bomzon
    • 2
  1. 1.University-MRC Circulation Research Unit and Departments of Physiology and MedicineUniversity of the Witwatersrand Medical SchoolJohannesburgSouth Africa
  2. 2.Department of General Physiology, School of DentistryUniversity of the WitwatersrandJohannesburgSouth Africa

Personalised recommendations