Skip to main content
SpringerLink
Log in

Spontaneous oscillations of systemic arterial pressure during cardiopulmonary bypass in man

  • Original Contributions
  • Published:
Basic Research in Cardiology Aims and scope Submit manuscript

Summary

Extracorporeal blood circulation (ECC) provides a steady flow and minimal pulmonary circulation in the absence of cardiac function. Oscillations of systemic arterial pressure were observed in 70 patients during ECC. At the onset of oscillations the frequency was as a rule 4 cycles per minute but depended on the temperature and showed a positive correlation with it. Correspondingly, the amplitude was about 6 mm Hg and depended on aortic pressure and showed a positive correlation with it. During the cooling phase of ECC the frequency decreased and the amplitude increased. The oscillations were independent of central venous pressure and ventilation. The oscillations disappeared either at the beginning of restitution of cardiac function or with decreasing arterial pressure caused by drug administration or rewarming. Arterial blood pressure oscillations have been described in experimental animals under various conditions but also in conscious man. The mechanisms underlying these oscillations are suggested to be nervous in origin, as is possible also in the present findings.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Anderson B, Kenney RA, Neil E (1950) The role of the chemoreceptors of the carotid and aortic regions in the production of Mayer waves. Acta Physiol Scand 20:203–220

    PubMed  Google Scholar 

  2. Dornhorst AC, Howard P, Leathart GL (1952) Respiratory variations in blood pressure. Circulation 6:553–558

    PubMed  Google Scholar 

  3. Ferretti R, Cherniak NS, Longobardo G, Levine OR, Morkin E, Singer DH, Fishman AP (1965) Systemic and pulmonary vasomotor waves. Am J Physiol 209:37–50

    PubMed  Google Scholar 

  4. Gedeon A, Odselius L, Lindblad LE, Wallin G (1983) A mathematical model and some measured characteristics of the carotid baroreceptor control of blood pressure in man. Med Biol Eng Comput 21:65–73

    PubMed  Google Scholar 

  5. Guyton AC, Harris JW (1951) Pressoreceptor-autonomic oscillation: a probable cause of vasomotor waves. Am J Physiol 165:158–166

    PubMed  Google Scholar 

  6. Guyton AC, Satterfield JH (1952) Vasomotor waves possibly resulting from CNS ischemic reflex oscillation. Am J Physiol 170:601–605

    PubMed  Google Scholar 

  7. Hering E (1869) Über den Einfluß der Atmung auf den Kreislauf. S-B Akad Wiss Wien, math-nat Kl 60:829–856

    Google Scholar 

  8. Kaminski RJ, Meyer GA, Winter DL (1970) Sympathetic unit activity associated with Mayer waves in the spinal dog. Am J Physiol 219:1768–1771

    PubMed  Google Scholar 

  9. Kenner T, Hinghofer-Szalkay H and Hinghofer-Szalkay L (1977) The continuous high-precision measurement of the density of flowing blood. Pflügers Arch 370:25–29

    Article  Google Scholar 

  10. Killip III T, (1962) Oscillation of blood flow and vascular resistance during Mayer waves. Circ Res 11:987–993

    PubMed  Google Scholar 

  11. Kollai M, Koizumi K (1981) Cardiovascular reflexes and inter-relationships between sympatheti and parasympathetic activity. J auton Nerv Syst 4:135–148

    Article  PubMed  Google Scholar 

  12. Mayer S (1876) Studien zur Physiologie des Herzens und Blutgefäße: V. Über spontane Blutdruck schwankungen. S-B Akad Wiss Wien, math-nat Kl 74:281–307

    Google Scholar 

  13. Preiss G, Iscoe S, Polosa C (1975) Analysis of a periodic breathing pattern associated with Maye waves. Am J Physiol 228:768–774

    PubMed  Google Scholar 

  14. Preiss G, Polosa C (1974) Patterns of sympathetic neuron activity associated with Mayer waves. Ann J Physiol 226:724–730

    Google Scholar 

  15. Quintin L, Whalley DG, Wynands JE, Morin JE, Burke J (1981) High dose fentanyl anaesthesis with oxygen for aorto-coronary bypass surgery. Can Anaesth Soc J 28:314–320

    PubMed  Google Scholar 

  16. Reves JG, Karp RB, Buttner EE, Tosone S, Smith LR, Samuelson PN, Kreusch GR, Oparic S (1982) Neuronal and adrenomedullary catecholamine release in response to cardiopulmonan bypass in man. Circulation 66:49–55

    PubMed  Google Scholar 

  17. Sebel PS, Bovill JG, Schellekens APM, Hawker CD (1981) Hormonal responses to high-dose fentanyl anaesthesia. A study in patients undergoing cardiac surgery. Br J Anaesth 53:941–948

    PubMed  Google Scholar 

  18. Sharpey-Schafer EP (1965) Effect of respiratory acts on the circulation. In: Hamilton WF (ed) Handbook of Physiology, sect 2, vol III. American Physiological Society, Washington, D.C., pp 1875–1886

    Google Scholar 

  19. Stanley TH, Philbin DM, Coggins CH (1979) Fentanyl-oxygen anaesthesia for coronary artery surgery: cardiovascular and anti-diuretic hormone responses. Can Anaesth Soc J 26:168–172

    PubMed  Google Scholar 

  20. Stanley TH, Webster LR (1978) Anaesthetic requirements and cardiovascular effect of fentanyl-oxygen and fentanyl-diazepam-oxygen anaesthesia in man. Anest Analg (Cleve) 57:411–416

    Google Scholar 

  21. Suwa K, Asahara H (1978) Vasomotor waves during cardiopulmonary bypass. Tohoku J Exp Med 125:45–51

    PubMed  Google Scholar 

  22. Taylor KM (1981) Why pulsatile flow during cardiopulmonary bypass. In: Longmore DB (ed) Towards safer cardiac surgery. MTP Press Ltd, Lancaster (England), pp 483–500

    Google Scholar 

  23. Taylor KM, Bairn WH, Russel M, Brannan JJ, Morton IJ (1979) Peripheral vascular resistance and angiotensin II levels during pulsatile and nonpulsatile cardiopulmonary bypass. Thorax 34:594–598

    PubMed  Google Scholar 

  24. Traube L (1865) Über periodische Thätigkeits-Äusserungen des vasomotorischen und Hemmungs-Nerven-Zentrums. Zentralbl med Wiss 56:881–908

    Google Scholar 

Download references

Author information

Author notes

  1. J. Timisjärvi M.D.

    Present address: Department of Physiology, University of Oulu, Kajaanintie 52 A, SF-90220, Oulu, (Finland)

Authors and Affiliations

  1. Department of Anaesthesiology, University Hospital of Oulu, Kajaanintie 52 A, SF-90220, Oulu, (Finland)

    V. Vainionpää, J. Timisjärvi M.D. & E. Saarela

  2. Department of Physiology, University of Oulu, Kajaanintie 52 A, SF-90220, Oulu, (Finland)

    V. Vainionpää & E. Saarela

Authors
  1. V. Vainionpää
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Timisjärvi M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Saarela
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vainionpää, V., Timisjärvi, J. & Saarela, E. Spontaneous oscillations of systemic arterial pressure during cardiopulmonary bypass in man. Basic Res Cardiol 80, 37–46 (1985). https://doi.org/10.1007/BF01906742

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01906742

Key words

Search

Navigation