Journal of thermal analysis

, Volume 15, Issue 2, pp 257–260 | Cite as

Thermoanalytical studies of organic compounds. part V

Rearrangement of acylated 3-hydroxy-1,2-benzisoxazoles
  • E. Domagalina
  • T. Sławik


This paper deals with the thermal analysis of the new benzoyl, methoxy- and ethoxycarbonyl-3-hydroxybenzisoxazoles by means of derivatograph. In the serial stages of tautomeric, isomeric and decarboxylic transformation, the newN-acylated benzisoxazolin-3-ones, benzoxazolin-2-ones and 3-alkylbenzoxazolin-2-ones were obtained.


Polymer Physical Chemistry Inorganic Chemistry Organic Compound Thermal Analysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Le comportement thermique de nouveaux benzoyl, méthoxy et éthoxycarbonyl-3-hydroxybenzisoxazoles a été étudié à l'aide d'un Derivatograph. Lors des étapes successives correspondant aux transformations tautomères, isomères et de décarboxylation, il se forme de nouvelles N-acétylées benzisoxazoline-3-ones, benzoxazoline-2-ones et 3-alkylbenzoxazoline-2-ones.


Der Artikel befasst sich mit der Thermoanalyse der neuen Benzoyl-, Methoxy- und Äthoxycarbonyl-3-hydroxybenzisoxazolen unter Anwendung der derivatographischen Methode. Die neuen N-acylierten Benzisoxazolin-3-one, Benzoxazolin-2-one und 3-Alkylbenzoxazolin-2-one wurden an Hand der Stufenfolge tautomerer, isomerer und Decarboxilierungs-Umwandlungen erhalten.


Статья касается терм ического анализа нов ых бензоил-, метокси- и это ксикарбонил-3-оксибен зоизоксазолов этоксикарбонил-3-окси бензоизоксазолов с помощью дериватогр афического метода. В р езультате нескольких стадий таутомерного, изомерного превраще ний, декарбоксилировани я, былиполучены новые N-aилированные бе нзоизоксазолин-3-оя, бензоксазолин-2-он и 3-ал килбензоксазолин-2-он.


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  1. 1.
    C. K. Cain andA. P. Roszkowski, Psychopharmacological Agents, Vol. I,M. Gordon, Ed. Academic Press, New York 1964, p. 325.Google Scholar
  2. 2.
    Ch. Lespagnol andA. Marcincal-Lefebvre, Chim. Ther., 2 (1967) 395.Google Scholar
  3. 3.
    J. Sam andJ. L. Valentine, J. Pharm. Sci., 58 (1969) 1043.PubMedGoogle Scholar
  4. 4.
    H. Böshagen, Ber., 100 (1967) 954, 3326.Google Scholar
  5. 5.
    H. Böshagen andW. Geiger, Ber., 102 (1969) 3775.Google Scholar
  6. 6.
    H. Böshagen andW. Geiger, Ber., 103 (1970) 123.Google Scholar
  7. 7.
    F. Paulik, J. Paulik andL. Erdey, Talanta, 13 (1966) 1405.CrossRefGoogle Scholar
  8. 8.
    E. Domagalina, T. Sławik, Folia Soc. Sci. Lub., Ser. C. 13 (1972) 13, 31.Google Scholar
  9. 9.
    E. Domagalina andT. Sławik, Ann. UMCS. AA, 29 (30) (1974) 331.Google Scholar
  10. 10.
    E. Domagalina andT. Sławik, Acta Pol. Pharm., 33 (1976) 623.PubMedGoogle Scholar
  11. 11.
    E. Domagalina andT. Sławik, Pol. J. Pharmacol. Pharm., 30 (1978) 717PubMedGoogle Scholar
  12. 12.
    Y.Nitta and F.Yoneda, Jap. Patent, 1467, 1964; CA. 66 (1967) 105000.Google Scholar

Copyright information

© Akadémiai Kiadó 1979

Authors and Affiliations

  • E. Domagalina
    • 1
  • T. Sławik
    • 1
  1. 1.Institute of Pharmaceutical ChemistryMedical AcademyLublinPoland

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