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The effects of prostaglandin E1 on the systemic and pulmonary circulations of intact dogs. The influence of urethane and pentobarbital anesthesia

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  • Pharmacologica
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Zusammenfassung

Es wird gezeigt, dass Phenobarbital- und Urethan-Anästhesie nach Infusion von PGE1 in den Kreislauf normaler Hunde verschiedene hämodynamische Reaktionen (Herzminutenvolumen, Herzfrequenz, Durchblutung der Peripherie) verursacht.

Die Intrakoronarinfusion von PGE1 mit der Narkose ergab einen negativ chronotropen und einen negativ inotropen Effekt.

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Authors and Affiliations

  1. Department of Medicine of the Tulane University, School of Medicine, USA

    T. D. Giles, A. C. Quiroz & G. E. Burch

  2. Charity Hospital of Louisiana, New Orleans

    G. E. Burch

Authors
  1. T. D. Giles
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  2. A. C. Quiroz
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  3. G. E. Burch
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Additional information

Supported by grants No. HE-06769 from the National Heart Institutes of the U.S. Public Health Service, the Rudolph Matas Memorial Fund for the Kate Prewitt Hess Laboratory and the Rowell A. Billups Fund for Research in Heart Disease.

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Giles, T.D., Quiroz, A.C. & Burch, G.E. The effects of prostaglandin E1 on the systemic and pulmonary circulations of intact dogs. The influence of urethane and pentobarbital anesthesia. Experientia 25, 1056–1058 (1969). https://doi.org/10.1007/BF01901427

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  • DOI: https://doi.org/10.1007/BF01901427

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