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Sodium concentration and the effect of angiotensin II on iieal smooth muscle

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Zusammenfassung

Die kontraktile Reaktion des isolierten Meerschweinchen-Ileums auf Angiotensin II variierte direkt mit der Natriumkonzentration der Nährflüssigkeit, nicht aber bei ACh; Atropin (10−6 g/ml) reduzierte die Wirkung auf Angiotensin um 60–70% und hob die Wirkung auf äquivalente Mengen von ACh auf. In atropinhaltiger Ringerlösung potenzierte ein hoher Natriumgehalt (+ 30 meq./l) die Reaktion auf Angiotensin zehnfach.

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  1. Howard Florey Laboratories of Experimental Physiology, Department of Physiology, University of Melbourne, Parkville, N.2, Victoria, Australia

    J. R. Blair-West & J. S. McKenzie

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  1. J. R. Blair-West
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  2. J. S. McKenzie
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Blair-West, J.R., McKenzie, J.S. Sodium concentration and the effect of angiotensin II on iieal smooth muscle. Experientia 22, 291–292 (1966). https://doi.org/10.1007/BF01900453

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