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Different localization of reserpine and tyramine within the 5-hydroxytryptamine organelles of blood platelets

  • Specialia
  • Chimica, Biochimica, Biophysica
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Zusammenfassung

Die subzelluläre Lokalisation von Reserpin und Tyramin in Blutplättchen von Kaninchen erfolgt in vitro und in vivo grösstenteils in den 5-Hydroxytryptamin (5HT)-Organellen. Dabei reichert sich Reserpin vorwiegend in der Membran, Tyramin hauptsächlich im Inneren der Organellen an. Es wird vermutet, dass Reserpin in bezug auf 5HT-Freisetzung an der Membran und Tyramin im Inneren der 5HT-Organellen angreift.

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Authors and Affiliations

  1. Forschungsabteilung der F. Hoffmann-La Roche and Co. AG, CH-4002, Basel, Switzerland

    M. Da Prada & A. Pletscher

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  1. M. Da Prada
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  2. A. Pletscher
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Da Prada, M., Pletscher, A. Different localization of reserpine and tyramine within the 5-hydroxytryptamine organelles of blood platelets. Experientia 25, 923–924 (1969). https://doi.org/10.1007/BF01898064

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  • DOI: https://doi.org/10.1007/BF01898064

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