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Structure activity relationships of some centrally active dialkyl substituted propanediol sulfites

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Une étude de 2-2-dialkyl-1-3-propanediol esters cyclique d'acide sulfureux constatait des filiations structure activité très interessantes. Avec un petit ralongant de la chaîne alkyl il est changé d'un stimulant système nerveux central (dimethyl, diethyl, et le pentaerythritol disulfite) à un dépressant système nerveux central fort modérément.

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  1. Research Center, Pitman-Moore Division, The Dow Chemical Company, Indianapolis, Indiana, USA

    L. C. Weaver, W. R. Jones & E. R. Bockstahler

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  1. L. C. Weaver
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  2. W. R. Jones
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  3. E. R. Bockstahler
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Weaver, L.C., Jones, W.R. & Bockstahler, E.R. Structure activity relationships of some centrally active dialkyl substituted propanediol sulfites. Experientia 22, 15–16 (1966). https://doi.org/10.1007/BF01897740

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