, Volume 22, Issue 3, pp 182–183 | Cite as

Effet des analgésiques non narcotiques sur l'hypotension due à la bradykinine

  • B. Vargaftig


Hypotension, induced by intravenous injections of bradykinin in the rabbit, was studied after nontoxic doses of non-narcotic analgesics and other drugs. Non-narcotic analgesics accelerated the speed of return to 50% normal blood pressure, whereas morphine, cyproheptadine, dexamethasone and hydrocortisone had no effect. Phentolamine-treated animals reacted similarly. This acceleration appears to be due to a specific antagonism of the non-narcotic analgesics and not to a liberation of adrenalin.

Copyright information

© Birkhäuser-Verlag 1966

Authors and Affiliations

  • B. Vargaftig
    • 1
  1. 1.Laboratoires EndopancrineEragny-sur-EpteOiseFrance

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