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Synthesis and properties of 1-deamino-, 9-decarboxy- and 1-deamino-9-decarboxy-bradykinin

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  • Chimica. Biochimica. Biophysica
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Zusammenfassung

Es wird über die Synthese von 1-Deamino-bradykinin, 9-Decarboxy-bradykinin und 1-Deamino-9-decarboxy-bradykinin und über deren biologische Aktivität berichtet. Nach dem verwendeten Testsystem scheint die endständige Carboxylgruppe für die Aktivität bedeutsamer zu sein als die endständige Aminogruppe.

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Authors and Affiliations

  1. Chemical Research Department, F. Hoffmann-La Roche Co., Ltd., Basel, Switzerland

    W. D. Johnson, H. D. Law & R. O. Studer

  2. Department of Chemistry and Biology, Liverpool Regional College of Technology, UK

    W. D. Johnson & H. D. Law

  3. Chemical Research Department, F. Hoffmann-La Roche & Co., Ltd., Basle, Switzerland

    R. O. Studer

Authors
  1. W. D. Johnson
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  2. H. D. Law
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  3. R. O. Studer
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Additional information

See H.Schröder and K.Lübke,The Peptides (Academic Press, New York 1966), vol. 2, p. 65.

Part of the PhD Thesis of W. D.Johnson.

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Johnson, W.D., Law, H.D. & Studer, R.O. Synthesis and properties of 1-deamino-, 9-decarboxy- and 1-deamino-9-decarboxy-bradykinin. Experientia 25, 573–574 (1969). https://doi.org/10.1007/BF01896515

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  • DOI: https://doi.org/10.1007/BF01896515

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