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Enterohepatischer Kreislauf von 7α-3H-DHEA-14C-Glukuronosid und 7α-3H-DHEA-35S-Sulfat beim Meerschweinchen

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Summary

By infusing doubly labelled conjugates into the duodenum or into a mesenteric vein it could be demonstrated that DHEA-sulfate passes the intestinal wall as well as the liver nearly without hydrolysis. However, most of the glucuronoside is hydrolysed in the intestine and reconjugated as sulfate.

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Authors and Affiliations

  1. Endokrinologische Abteilung des Hygiene-Institutes der Universität des Saarlandes, Homburg, Saar, Deutschland

    P. Knapstein & G. W. Oertel

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  1. P. Knapstein
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  2. G. W. Oertel
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Die vorliegende Arbeit wurde mit Unterstützung der Deutschen Forschungsgemeinschaft durchgeführt.

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Knapstein, P., Oertel, G.W. Enterohepatischer Kreislauf von 7α-3H-DHEA-14C-Glukuronosid und 7α-3H-DHEA-35S-Sulfat beim Meerschweinchen. Experientia 22, 577–578 (1966). https://doi.org/10.1007/BF01895260

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  • DOI: https://doi.org/10.1007/BF01895260

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